Three years ago, Dax Hoffman and colleagues in Dan Johnston’s group reported (Hoffman 1997) a particular class of voltage-gated K+ channels-fast-inactivating (A-type) channels- have a surprising distribution in hippocampal CA1 pyramids: A-channel density increases steeply along the apical dendrite, being >5-fold concentrated in the distal dendrites set alongside the soma. Furthermore, a change in the… Continue reading Three years ago, Dax Hoffman and colleagues in Dan Johnston’s group